Titanium dioxide LD50: Not available. LC50: Not available.

Insoluble in cold water, hydrochloric acid, nitric acid, diluted sulfuric acid, organic solvents. Soluble in hot concentrated sulfuric acid, hydrofluoric acid, alkali

Potential Acute Health Effects:
Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS:
A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC.
MUTAGENIC EFFECTS:
Mutagenic for mammalian somatic cells.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance may be toxic to lungs, upper respiratory tract. Repeated or prolonged exposure to the substance can produce target organs damage.

Eye Contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for atleast 15 minutes. Get medical attention if irritation occurs.
Skin Contact:
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Serious Skin Contact: Not available.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Serious Inhalation: Not available.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
Serious Ingestion: Not available.

Flammability of the Product: Non-flammable.
Auto-Ignition Temperature: Not applicable.
Flash Points: Not applicable.
Flammable Limits: Not applicable.
Products of Combustion: Not available.
Fire Hazards in Presence of Various Substances: of metals
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions: Not applicable.
Special Remarks on Fire Hazards:
Not combustible.
A violent or incandescent reaction with metals (aluminum, calcium, magnesium, potassium, sodium, zinc, and lithium) may occur at high temperatures.
Special Remarks on Explosion Hazards: Not available.

Accidental Release Measures
Small Spill:
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill:
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
Handling and Storage
Precautions:
Do not breathe dust. Wear suitable protective clothing. If you feel unwell, seek medical attention and show the label when possible. Keep away from incompatibles such as acids.
Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.

Engineering Controls:
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection:
Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits:
TWA: 15 (mg/m3) from OSHA (PEL) [United States] Inhalation Total.
TWA: 10 (mg/m3) from ACGIH (TLV) [United States] Inhalation Total.
TWA: 4 [United Kingdom (UK)] Inhalation Respirable.
TWA: 10 [United Kingdom (UK)] Inhalation Total.Consult local authorities for acceptable exposure limits.

Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Incompatible materials
Incompatibility with various substances:
Reactive with acids.
Slightly reactive to reactive with metals.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity:
Reaction of titanium dioxide and lithium occurs around 200 C with a flash of light; the temperature can reach 900 degrees C. A violent or incandescent reaction with metals (aluminum, calcium, magnesium, potassium, sodium, zinc, and lithium) may occur at high temperatures.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.

Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation:
The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.

DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.

Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental control regulations.